Linagliptin

Linagliptin (BI-1356, trade names Tradjenta (US), Trajenta (worldwide)) is a DPP-4 inhibitor developed by Boehringer Ingelheim for treatment of type II diabetes.

Linagliptin (once-daily) was approved by the U.S. Food and Drug Administration (FDA) on 2 May 2011 for treatment of type II diabetes. It is being marketed by Boehringer Ingelheim and Lilly.

Medical uses

Results in 2010 from a Phase III clinical trial of linagliptin showed that the drug can effectively reduce blood sugar.

Mechanism of action

TRADJENTA belongs to a class of drugs called DPP-4 inhibitors. DPP-4 inhibitors work by increasing hormones that stimulate your pancreas to produce more insulin and stimulate your liver to produce less glucose.In other words, TRADJENTA, along with diet and exercise, can help your body produce more insulin and less sugar. Managing your sugar can mean a lower A1C – and that's an important goal for anyone with type 2 diabetes.

products details:

1.Product name: Linagliptin

2.CAS No.:668270-12-0

3.Purity: 99% min

4.Storage information: Store in Cool and dry .place, keep away from strong light, high temperature

5.Usage:Pharmaceutical raw materials

6.Transportation：by air express delivery(DHL,FedEx,EMS ect.) or sea shipping (FOB,CIF,CFR,CNF ect.)

7.Sample：sample can be supplied if you inquiry 

8.Price: we will give you the best price !

Specification:

Product Name	Linagliptin       CAS 668270-12-0
Batch No.	150120		Quantity		25kgs
Test date	2015.01.20		Report date		2015.01.27
Expire date	2017.01.20		Standard		In-house
Result of Analysis
Items		Specifications		Results
Appearance		White or off-white crystalline powder		Conforms
HPLC		The retention time of the major peaking the chromatogram of the sample corresponds to that exhibited by the working standard		Conforms
Loss on drying		No more than 1.0%		0.40%
Residue on Ignition		No more than 0.1%		0.02%
Heavy Metals		No more than 20ppm		<10ppm
Related substances		Total impurities no more than 1.0%		0.50%
		Single impurity no more than 0.5%		Conforms
Residual solvents		Ethyl acetate No more than 0.1%		Conforms
		Ethanol No more than 0.1%		Conforms
Purity		No less than 99.0%		99.50%
Conclusion		Conforms to the In-house standard.

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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body