2016年10月20日星期四

Oxcarbazepine


Oxcarbazepine is an anticonvulsant drug primarily used in the treatment of epilepsy. There is some evidence for oxcarbazepine as a mood-stabilizing agent and thus, it can be used as add-on therapy for bipolar disorder in patients that have failed or are unable to tolerate approved treatments.

Common side effects include nausea, vomiting, dizziness, drowsiness, headache, double vision and trouble with walking. Although not common, anaphylaxis may occur. Due to its structural similarities to carbamazepine there is approximately a 25–30% chance of cross-reactivity between the two medications.

Oxcarbazepine is marketed as Trileptal by Novartis and available in some countries as a generic drug. There is also an extended-release formation marketed as Oxtellar XR by Supernus Pharmaceuticals.

Product Details
Product Name Oxcarbazepine
Molecular Formula C15H12N2O2
Molecular Weight 252.268
CAS Registry Number 28721-07-5
EINECS 249-188-8
Quality: ≥99%,impurities≤1.5%
Density 1.329g/cm3
Boiling point 457.2°C at 760 mmHg
Refractive index 1.661
Flash point 230.3°C
Vapour Pressur 1.52E-08mmHg at 25°C
nameOxcarbazepine
molecular formulaC15H12N2O2    
molecular weight252.268
InChIInChI=1/C15H12N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8H,9H2,(H2,16,19)
density 1.329g/cm3
boiling point 457.2°C at 760 mmHg  
flash point230.3°C  
steam vapour1.52E-08mmHg at 25°C
characterlight white  crystaline fine powder
Specification:


ITEMSSPECIFICATIONSRESULTS
AppearanceA white or almost white,crystalline powderConforms
IdentificationIR & UV & HPLCConforms
SolubilitySoluble in methanol and ethanol ,insoluble in waterConforms
Melting point222 ~ 228 ℃223 ~ 224 ℃
Loss on drying≤0.3%0.21%
Residue on Ignition≤0.2%
0.09%

Relative substanceCarbamazepine ≤0.2%0.14%
Unknow impurities ≤0.5%

<0.5%
Total impurities ≤1.0%0.64%
Assay≥99.0%

99.36%

ConclusiionThis product complied with the standard of Enterprise
Packaging & Shipping:

[Storage] Stored in a clean, cool and dry area; keep away from strong, direct light.

[Shelf Life] 2 years when properly stored.

[Packing]
Inner double plastic bags--25kg/Fiber drum (35*35*53cm, GW: 28kg, NW: 25kg, 0.06CBM);
Inner double plastic bags--5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg);
Inner double plastic bags--1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).

[Delivery] 5 working days after payment.

my contact infomation is:

Email: cloris_2016@tuskwei.com or

bettytuskwei@yahoo.com

Skype: betty_3451

Website: http://www.tuskwei.net/

Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body


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