Aesculetin (also known as esculetin, 6,7-dihydroxycoumarin and cichorigenin) is a derivative of coumarin. It is a natural lactone that derives from the intramolecular cyclization of a cinnamic acid derivative.
It is present in chicory and in many toxic and medicinal plants, in form of glycosides and caffeic acid conjugates.
Esculetin-containing preparations used systemically can have an anticoagulant effect and might interact with anticoagulent drugs such as warfarin.
This compound is used in some sunscreens, but there is evidence that it acts as a photosensitizer for DNA damage. The sodium salt of its methyl-derivative is used in dermatology for the treatment of varicose veins.
It is a blue fluorescence compound found in plants. Aesculin, the glucoside of aesculetin, will fluoresce under long wave ultraviolet light (360 nm). The hydrolysis of aesculin results in loss of this fluorescence. Aesculetin has the ability to quench the inner fluorescence of bovine serum albumin.
Aesculetin can be transformed into scopoletin (7-hydroxy-6-methoxycoumarin) and isoscopoletin (6-hydroxy-7-methoxycoumarin) through incubation with rat liver catechol-O-methyltransferase.
Product Details Showing:
English name:Esculetin
Orginal plant: Aesculushippocastanumlinn Tree bark
Purity:HPLC≥98%
Specification: 20mg/vial
CAS NO. :305-01-1
Appearance:white or light yellow needle crystal
Molecular formula:C9H6O4
Molecular weight:178.14
Functions :
1.Anti-inflammation, Anti-bacteria analgesia, Anti-arrhythmic, Anti-histaminic, antiphlogistic action similar to that of Vitamin P.
2.Esculetin, Anti-inflammation, Anti-bacteria,Ease pain, Anti-arrhythmic, Anti-histaminic,Esculetin is a glycosidecomposed of
glucose and a dihydroxycoumarin compound.
3.Esculetin is used in the manufacturing of pharmaceuticals with venotonic, capillary- strengthening and antiphlogistic action similar to that of Vitamin P.
4.Esculetin is a fluorescent dye that can be extracted from the leaves and bark of the horse chestnut tree.
Packing :
1~25kg: Packed in 1kg/bag or 5kg/bag with double plastic valve bag and Aluminum foil bag outside. Over 25kg: 25kg/drum with PE polyethylene double packing and cardboard barrels
Storage : Stored in cool and dry well-closed container, keep away from moisture and strong
light/heat.
MOQ : 1KG
Payment : T/T,L/C,Paypal,Western union
Certificate of analysis:
| Analysis | Specification | Results |
| Assay(HPLC) | Aesculetin≥98% | 98.05% |
| Appearance | Light yellow powder | Complies |
| Pesticides | Negative | Complies |
| Ash | ≤5.0% | 2.1% |
| Moisture | ≤5.0% | 1.15% |
| Heavy metals | ≤10ppm | Complies |
| Pb | ≤1.0ppm | Complies |
| As | ≤1.0ppm | Complies |
| Hg | ≤0.1ppm | Complies |
| Cd | ≤0.1ppm | Complies |
| Odor | Characteristic | Complies |
| Particle size | 100%through 80 mesh | Complies |
| Microbioiogical: | ||
| Total of bacteria | ≤1000cfu/g | Complies |
| Fungi | ≤100cfu/g | Complies |
| Salmgosella | Negative | Complies |
| Coli | Negative | Complies |
Storage Store in cool & dry place. Do not freeze.
Keep away from strong light and heat.
Shelf life 2 years when properly stored
| ||
my contact infomation is:
Email: cloris_2016@tuskwei.com or
bettytuskwei@yahoo.com
Skype: betty_3451
Website: http://www.tuskwei.net/
Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body
没有评论:
发表评论