2016年10月19日星期三

Oxyclozanide


Oxyclozanide is a salicylanilide anthelmintic. It is used in the treatment and control of fascioliasis in ruminants mainly domestic animals such as cattle, sheep, and goats. It mainly acts by uncoupling of oxidative phosphorylation in flukes.Along with niclosamide, another tapeworm drug, it has been recently found to display "strong in vivo and in vitro activity against methicillin-resistant Staphylococcus aureus (MRSA)".

Specifications

OXYCLOZANIDE 
Veterinary: Aquatic Animals 
GMP 
Standard: USP/EP/BP

OXYCLOZANIDE
CAS No.:2277-92-1
Molecular Formula :  C13H6Cl5NO3
Molecular Weight:401.46
Appearance: off-white  powder
Melting Point: 205 - 210 °C
Solubility: slightly soluble in water; soluble in acetone, ethanol; melting point 205 C.
Stability: Stable under ordinary conditions.

Specifications
1.GMP Approved 2.Quality Standard: USP/EP/BP 
3.CAS NO.: 2277-92-1

Synonyms: 
3,3',5,5',6-pentachloro-2'-hydroxy salicylanilide;
2 ,3,5-trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide;
CAS No.:2277-92-1
Molecular Formula :  C13H6Cl5NO3
Molecular Weight:401.46
EINECS NO.: 218-904-0

Assay: 98%  GMP Approve 
Quality Standard:  USP/EP/BP 

Appearance: off-white  powder
Melting Point: 205 - 210 C
Solubility: slightly soluble in water; soluble in acetone, ethanol; melting point 205 C.
Stability: Stable under ordinary conditions

General Description & Applications:
Oxyclozanide is a salicylanilide anthelmintic used in flukes and tapeworm segments in cattle and sheep.
Anthelmintic (also spelled  anthelminthic) is a chemical substance used to expel or destroy tapeworms in domestic animals. Some common anthelmintic active ingredients classified by chemical structure include;

Storage: in  airtight  and  cool place, away  from heat  and  light .


ESTSSPECIFICATIONSOBSERVATIONS
DescriptionA pale cream or cream coloured powder; odourless or almost odourless.A pale yellow colour powder, odourless.
SolubilityVery slightly soluble in water. Freely soluble in acetone, soluble in ethanol.Complies
Identification--
A) IRAs per BPComplies
B) UVAs per BPComplies
Melting RangeoCMelts between 208oC to 211oC208-210oC
Ionisable ChlorideNot more than 1.4 ml is required (0.25%).0.7 ml
Related Substances (By HPLC)As per BP VETComplies
Sulphated AshNot more than 0.2%0.10%
Loss on DryingNot more than 1.0%0.43%
Assay on dried basis, w/w98.0-101.0%99.68%

my contact infomation is:

Email: cloris_2016@tuskwei.com or

bettytuskwei@yahoo.com

Skype: betty_3451

Website: http://www.tuskwei.net/

Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body

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