Oxyclozanide is a salicylanilide anthelmintic. It is used in the treatment and control of fascioliasis in ruminants mainly domestic animals such as cattle, sheep, and goats. It mainly acts by uncoupling of oxidative phosphorylation in flukes.Along with niclosamide, another tapeworm drug, it has been recently found to display "strong in vivo and in vitro activity against methicillin-resistant Staphylococcus aureus (MRSA)".
Specifications
OXYCLOZANIDE
Veterinary: Aquatic Animals
GMP
Standard: USP/EP/BP
OXYCLOZANIDE
CAS No.:2277-92-1
Molecular Formula : C13H6Cl5NO3
Molecular Weight:401.46
Appearance: off-white powder
Melting Point: 205 - 210 °C
Solubility: slightly soluble in water; soluble in acetone, ethanol; melting point 205 C.
Stability: Stable under ordinary conditions.
Specifications
1.GMP Approved 2.Quality Standard: USP/EP/BP
3.CAS NO.: 2277-92-1
Synonyms:
3,3',5,5',6-pentachloro-2'-hydroxy salicylanilide;
2 ,3,5-trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide;
CAS No.:2277-92-1
Molecular Formula : C13H6Cl5NO3
Molecular Weight:401.46
EINECS NO.: 218-904-0
Assay: 98% GMP Approve
Quality Standard: USP/EP/BP
Appearance: off-white powder
Melting Point: 205 - 210 C
Solubility: slightly soluble in water; soluble in acetone, ethanol; melting point 205 C.
Stability: Stable under ordinary conditions
General Description & Applications:
Oxyclozanide is a salicylanilide anthelmintic used in flukes and tapeworm segments in cattle and sheep.
Anthelmintic (also spelled anthelminthic) is a chemical substance used to expel or destroy tapeworms in domestic animals. Some common anthelmintic active ingredients classified by chemical structure include;
Storage: in airtight and cool place, away from heat and light .
ESTS | SPECIFICATIONS | OBSERVATIONS |
Description | A pale cream or cream coloured powder; odourless or almost odourless. | A pale yellow colour powder, odourless. |
Solubility | Very slightly soluble in water. Freely soluble in acetone, soluble in ethanol. | Complies |
Identification | - | - |
A) IR | As per BP | Complies |
B) UV | As per BP | Complies |
Melting RangeoC | Melts between 208oC to 211oC | 208-210oC |
Ionisable Chloride | Not more than 1.4 ml is required (0.25%). | 0.7 ml |
Related Substances (By HPLC) | As per BP VET | Complies |
Sulphated Ash | Not more than 0.2% | 0.10% |
Loss on Drying | Not more than 1.0% | 0.43% |
Assay on dried basis, w/w | 98.0-101.0% | 99.68% |
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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body
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