2017年3月7日星期二

Tianeptina

Tianeptine (brand names Stablon, Coaxil, Tatinol, Tianeurax and Salymbra) is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.

Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).

Tianeptine is a low-affinity full agonist at the μ-opioid and δ-opioid receptors with negligible effect at the κ-opioid receptors. μ-Opioid agonists typically induce euphoria, and in accordance, tianeptine does so at high doses well above the normal therapeutic range.

Product Introduction: 
Place of orgin: China
Specification:
1.Product name:Tianeptine
2.CAS No.:66981-73-5
3.Purity: 99% min
Synonyms:View MoreCOAXIL; Tianeptina; Tianeotine; Tianeptinum; Tianeptine-d4; Tianeptineacid; Tianeptina [inn-spanish]
Storage information: Store in Cool and dry .place, keep away from strong light, high temperature
Usage: intermediate,fine chemical
Transportation:by air express delivery(DHL,FedEx,EMS ect.) or sea shipping (FOB,CIF,CFR,CNF ect.)
Sample:sample can be supplied if you inquiry 
Price: we will give you the best price!

Specification:


Packaging & Shipping

Packing:1:We adopt different packing methods,According to the product .
                      Poly Bag Inner, Woven Bag outer,kraft paper bags,
                      Fibra bag or Drum and so on.
                 2:According to customer's requirement!

Shipping:We supply different transportations.
                   International courier like(TNT UPS DHL FEDEX)
                   We also supply by Air,by Sea
Tianeptine 3.jpg

my contact infomation is:
Email: bettyapi@aliyun.com or bettyapi1989@yahoo.com
Skype: bettyapi1989

Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body

Coaxil

Tianeptine (brand names Stablon, Coaxil, Tatinol, Tianeurax and Salymbra) is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.

Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).

Tianeptine is a low-affinity full agonist at the μ-opioid and δ-opioid receptors with negligible effect at the κ-opioid receptors. μ-Opioid agonists typically induce euphoria, and in accordance, tianeptine does so at high doses well above the normal therapeutic range.

Product Introduction: 
Place of orgin: China
Specification:
1.Product name:Tianeptine
2.CAS No.:66981-73-5
3.Purity: 99% min
Synonyms:View MoreCOAXIL; Tianeptina; Tianeotine; Tianeptinum; Tianeptine-d4; Tianeptineacid; Tianeptina [inn-spanish]
Storage information: Store in Cool and dry .place, keep away from strong light, high temperature
Usage: intermediate,fine chemical
Transportation:by air express delivery(DHL,FedEx,EMS ect.) or sea shipping (FOB,CIF,CFR,CNF ect.)
Sample:sample can be supplied if you inquiry 
Price: we will give you the best price!

Specification:


Packaging & Shipping

Packing:1:We adopt different packing methods,According to the product .
                      Poly Bag Inner, Woven Bag outer,kraft paper bags,
                      Fibra bag or Drum and so on.
                 2:According to customer's requirement!

Shipping:We supply different transportations.
                   International courier like(TNT UPS DHL FEDEX)
                   We also supply by Air,by Sea
Tianeptine 3.jpg

my contact infomation is:
Email: bettyapi@aliyun.com or bettyapi1989@yahoo.com
Skype: bettyapi1989

Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body

Coaxil

Tianeptine (brand names Stablon, Coaxil, Tatinol, Tianeurax and Salymbra) is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.

Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).

Tianeptine is a low-affinity full agonist at the μ-opioid and δ-opioid receptors with negligible effect at the κ-opioid receptors. μ-Opioid agonists typically induce euphoria, and in accordance, tianeptine does so at high doses well above the normal therapeutic range.

Product Introduction: 
Place of orgin: China
Specification:
1.Product name:Tianeptine
2.CAS No.:66981-73-5
3.Purity: 99% min
Synonyms:View MoreCOAXIL; Tianeptina; Tianeotine; Tianeptinum; Tianeptine-d4; Tianeptineacid; Tianeptina [inn-spanish]
Storage information: Store in Cool and dry .place, keep away from strong light, high temperature
Usage: intermediate,fine chemical
Transportation:by air express delivery(DHL,FedEx,EMS ect.) or sea shipping (FOB,CIF,CFR,CNF ect.)
Sample:sample can be supplied if you inquiry 
Price: we will give you the best price!

Specification:


Packaging & Shipping

Packing:1:We adopt different packing methods,According to the product .
                      Poly Bag Inner, Woven Bag outer,kraft paper bags,
                      Fibra bag or Drum and so on.
                 2:According to customer's requirement!

Shipping:We supply different transportations.
                   International courier like(TNT UPS DHL FEDEX)
                   We also supply by Air,by Sea
Tianeptine 3.jpg

my contact infomation is:
Email: bettyapi@aliyun.com or bettyapi1989@yahoo.com
Skype: bettyapi1989

Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body

Stablon

Tianeptine (brand names Stablon, Coaxil, Tatinol, Tianeurax and Salymbra) is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.

Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).

Tianeptine is a low-affinity full agonist at the μ-opioid and δ-opioid receptors with negligible effect at the κ-opioid receptors. μ-Opioid agonists typically induce euphoria, and in accordance, tianeptine does so at high doses well above the normal therapeutic range.

Product Introduction: 
Place of orgin: China
Specification:
1.Product name:Tianeptine
2.CAS No.:66981-73-5
3.Purity: 99% min
Synonyms:View MoreCOAXIL; Tianeptina; Tianeotine; Tianeptinum; Tianeptine-d4; Tianeptineacid; Tianeptina [inn-spanish]
Storage information: Store in Cool and dry .place, keep away from strong light, high temperature
Usage: intermediate,fine chemical
Transportation:by air express delivery(DHL,FedEx,EMS ect.) or sea shipping (FOB,CIF,CFR,CNF ect.)
Sample:sample can be supplied if you inquiry 
Price: we will give you the best price!

Specification:


Packaging & Shipping

Packing:1:We adopt different packing methods,According to the product .
                      Poly Bag Inner, Woven Bag outer,kraft paper bags,
                      Fibra bag or Drum and so on.
                 2:According to customer's requirement!

Shipping:We supply different transportations.
                   International courier like(TNT UPS DHL FEDEX)
                   We also supply by Air,by Sea
Tianeptine 3.jpg

my contact infomation is:
Email: bettyapi@aliyun.com or bettyapi1989@yahoo.com
Skype: bettyapi1989

Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body

Tianeptine

Tianeptine (brand names Stablon, Coaxil, Tatinol, Tianeurax and Salymbra) is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.

Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).

Tianeptine is a low-affinity full agonist at the μ-opioid and δ-opioid receptors with negligible effect at the κ-opioid receptors. μ-Opioid agonists typically induce euphoria, and in accordance, tianeptine does so at high doses well above the normal therapeutic range.

Product Introduction: 
Place of orgin: China
Specification:
1.Product name:Tianeptine
2.CAS No.:66981-73-5
3.Purity: 99% min
Synonyms:View MoreCOAXIL; Tianeptina; Tianeotine; Tianeptinum; Tianeptine-d4; Tianeptineacid; Tianeptina [inn-spanish]
Storage information: Store in Cool and dry .place, keep away from strong light, high temperature
Usage: intermediate,fine chemical
Transportation:by air express delivery(DHL,FedEx,EMS ect.) or sea shipping (FOB,CIF,CFR,CNF ect.)
Sample:sample can be supplied if you inquiry 
Price: we will give you the best price!

Specification:


Packaging & Shipping

Packing:1:We adopt different packing methods,According to the product .
                      Poly Bag Inner, Woven Bag outer,kraft paper bags,
                      Fibra bag or Drum and so on.
                 2:According to customer's requirement!

Shipping:We supply different transportations.
                   International courier like(TNT UPS DHL FEDEX)
                   We also supply by Air,by Sea





my contact infomation is:
Email: bettyapi@aliyun.com or bettyapi1989@yahoo.com
Skype: bettyapi1989

Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body

2017年3月6日星期一

ADENINE-9-BETA-D-RIBOFURANOSIDE

Adenosine is a purine nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond. Adenosine is widely found in nature and plays an important role in biochemical processes, such as energy transfer—as adenosine triphosphate (ATP) and adenosine diphosphate (ADP)—as well as in signal transduction as cyclic adenosine monophosphate (cAMP). It is also a neuromodulator, believed to play a role in promoting sleep and suppressing arousal. Adenosine also plays a role in regulation of blood flow to various organs through vasodilation.

In addition to adenosine's endogenous forms, it is also used as a medication, specifically, as an antiarrhythmic agent, to treat a number of forms of supraventricular tachycardia that do not improve with vagal maneuvers. Common side effects include chest pain, feeling faint, shortness of breath along with tingling of the senses . Serious side effects include a worsening dysrhythmia and low blood pressure. It appears to be safe in pregnancy.

Adenosine – cosmetics grade
Product No.: SB001-1
CAS No.: 58-61-7
Other name:Adenine riboside
Synonyms: D-ADENOSINE;AR;(2R,3R,4S,5R)-2-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL;9-BETA-D-RIBOFURANOSYLADENINE;ADENINENUCLEOSIDE;ADENINE RIBOSIDE;ADENOSINE;ADENINE-9-BETA-D-RIBOFURANOSIDE
Formular: C10H13N5O4
Molecular weight: 267.24
Appearance: a white or almost white crystalline powder
Loss on drying: ≤1.0%
Assay: ≥99%
Endotoxin: ≤1000EU/g
Total aerobic limits:≤1000cfu/g
Total mold limits:≤100cfu/g
Escherichia coli: Not detected

Application
Adenosine is an endogenous nucleoside throughout the human cells directly into the myocardium by phosphorylation generates adenylate involved in myocardial energy metabolism. Adenosine also attend the expansion of coronary vessels, increasing blood flow.
Adenosine plays a physiological role on the cardiovascular system and the body's many systems and organizations. Adenosine is used in the synthesis adenosine triphosphate, adenosine (ATP), adenine, adenosine, the vidarabine important intermediates.
Packing
25kg/drum or as per your requirement
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Stored in a cool, dry, well-ventilated area. Away from incompatible substances. Store protected from moisture.

Specification of Adenosine 58-61-7
1. Molecular formula: C10H13N5O4
2. Molecular weight: 267.24
3. CAS No.: 58-61-7
4. Melting point: 233-238°C
5. Specific rotation: -68.0°- -72.0°
6. Acidity or alkalinity: complies with USP28
7. Loss on drying: ≤0.5%
8. Residue on ignition: ≤0.1%
9. Heavy metals: ≤0.001%
10. Limit of ammonia: ≤0.0004%
11. Limit of chloride: ≤0.007%
12. Limit of sulfate: ≤0.02%
13. Total impurities: ≤0.5%
14. Each of guanosine, inosine, and uridine ≤0.1%
15. Adenine: ≤0.2%
16. Assay: 99.0-101.0%
17. Complies with USP28
18. Packing: 20kg/barrel
19. Storage: Keep dry, stable at room temperature.
Indexstandards
Assay99%min
Melting point °C-68.0°C to –72.0°C
Acidity or alkalinity
Solution appears blue-violet color and yellow color

Loss on drying,%≤0.5
Heavy metals(Pb), %≤0.001
Limit of ammonia,%≤0.0004
Limit of chloride(Cl),%≤0.007
Limit of sulfate(SO4),%≤0.02
Chromatographic purity, %
Guanosine, %
Inosine, %
Ruidine, %
Adenine, %
Total impurities, %
≤0.1
≤0.1
≤0.1
≤0.2
≤0.5

my contact infomation is:
Email: bettyapi@aliyun.com or bettyapi1989@yahoo.com
Skype: bettyapi1989

Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body

ADENOSINE

Adenosine is a purine nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond. Adenosine is widely found in nature and plays an important role in biochemical processes, such as energy transfer—as adenosine triphosphate (ATP) and adenosine diphosphate (ADP)—as well as in signal transduction as cyclic adenosine monophosphate (cAMP). It is also a neuromodulator, believed to play a role in promoting sleep and suppressing arousal. Adenosine also plays a role in regulation of blood flow to various organs through vasodilation.

In addition to adenosine's endogenous forms, it is also used as a medication, specifically, as an antiarrhythmic agent, to treat a number of forms of supraventricular tachycardia that do not improve with vagal maneuvers. Common side effects include chest pain, feeling faint, shortness of breath along with tingling of the senses . Serious side effects include a worsening dysrhythmia and low blood pressure. It appears to be safe in pregnancy.

Adenosine – cosmetics grade
Product No.: SB001-1
CAS No.: 58-61-7
Other name:Adenine riboside
Synonyms: D-ADENOSINE;AR;(2R,3R,4S,5R)-2-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL;9-BETA-D-RIBOFURANOSYLADENINE;ADENINENUCLEOSIDE;ADENINE RIBOSIDE;ADENOSINE;ADENINE-9-BETA-D-RIBOFURANOSIDE
Formular: C10H13N5O4
Molecular weight: 267.24
Appearance: a white or almost white crystalline powder
Loss on drying: ≤1.0%
Assay: ≥99%
Endotoxin: ≤1000EU/g
Total aerobic limits:≤1000cfu/g
Total mold limits:≤100cfu/g
Escherichia coli: Not detected

Application
Adenosine is an endogenous nucleoside throughout the human cells directly into the myocardium by phosphorylation generates adenylate involved in myocardial energy metabolism. Adenosine also attend the expansion of coronary vessels, increasing blood flow.
Adenosine plays a physiological role on the cardiovascular system and the body's many systems and organizations. Adenosine is used in the synthesis adenosine triphosphate, adenosine (ATP), adenine, adenosine, the vidarabine important intermediates.
Packing
25kg/drum or as per your requirement
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Stored in a cool, dry, well-ventilated area. Away from incompatible substances. Store protected from moisture.

Specification of Adenosine 58-61-7
1. Molecular formula: C10H13N5O4
2. Molecular weight: 267.24
3. CAS No.: 58-61-7
4. Melting point: 233-238°C
5. Specific rotation: -68.0°- -72.0°
6. Acidity or alkalinity: complies with USP28
7. Loss on drying: ≤0.5%
8. Residue on ignition: ≤0.1%
9. Heavy metals: ≤0.001%
10. Limit of ammonia: ≤0.0004%
11. Limit of chloride: ≤0.007%
12. Limit of sulfate: ≤0.02%
13. Total impurities: ≤0.5%
14. Each of guanosine, inosine, and uridine ≤0.1%
15. Adenine: ≤0.2%
16. Assay: 99.0-101.0%
17. Complies with USP28
18. Packing: 20kg/barrel
19. Storage: Keep dry, stable at room temperature.
Indexstandards
Assay99%min
Melting point °C-68.0°C to –72.0°C
Acidity or alkalinity
Solution appears blue-violet color and yellow color

Loss on drying,%≤0.5
Heavy metals(Pb), %≤0.001
Limit of ammonia,%≤0.0004
Limit of chloride(Cl),%≤0.007
Limit of sulfate(SO4),%≤0.02
Chromatographic purity, %
Guanosine, %
Inosine, %
Ruidine, %
Adenine, %
Total impurities, %
≤0.1
≤0.1
≤0.1
≤0.2
≤0.5

my contact infomation is:
Email: bettyapi@aliyun.com or bettyapi1989@yahoo.com
Skype: bettyapi1989

Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body