Mifepristone

Mifepristone, also known as RU-486, is a medication typically used with misoprostol to bring about an abortion. This combination is more than 95% effective during the first 50 days of pregnancy. It is also effective in the second trimester of pregnancy. Two weeks after use effectiveness should be verified. It is taken by mouth.

Common side effects include abdominal pain, feeling tired, and vaginal bleeding. Serious side effects may include heavy vaginal bleeding, bacterial infection, and a malformed baby if the pregnancy does not end. If used, appropriate follow up care needs to be available. Mifepristone works by blocking the effects of progesterone and causing contractions of the uterus.

Medical uses

Abortion

Mifepristone followed by a prostaglandin analog (misoprostol or gemeprost) is used for medical abortion.

A 2011 evidence-based clinical guideline by the Royal College of Obstetricians and Gynaecologists (RCOG) says medical abortion using mifepristone followed by the prostaglandin analog misoprostol is effective and appropriate at any gestational age.[13]

A 2012 technical and policy guidance book and a 2014 clinical practice handbook by the World Health Organization (WHO) recommend mifepristone followed by the prostaglandin analog misoprostol for first and second trimester medical abortions.

2013 and 2014 practice bulletins by the American College of Obstetricians and Gynecologists (ACOG) recommend mifepristone followed by the prostaglandin analog misoprostol for first and second trimester medical abortions.

Mifepristone alone results in abortion within two weeks of 54% to 92% of pregnancies.

Cushing's syndrome

Mifepristone is used for the medical treatment of high blood sugar (hyperglycemia) caused by high cortisol levels in the blood (hypercortisolism) in adults with endogenous Cushing’s syndrome who have type 2 diabetes mellitus or glucose intolerance and have failed surgery or cannot have surgery.

1.product details：

Name  Mifepristone

CAS 84371-65-3

Formula  C29H35NO2

Appearance White powder

purity 99%MIN

Assay HPLC;LC-MS;HNRM

Minimum order quantity  100 gram

Packing aluminum foil bag

stock   Mass stock

application

Mifepristone (or RU-486) is a synthetic steroid compound with both antiprogesterone and antiglucocorticoid properties. The compound is a 19-nor steroid with substitutions at positions C11 and C17 (17 beta-hydroxy-11 beta-[4-dimethylamino phenyl] 17 alpha-[1-propynyl]estra-4,9-dien-3-one), which antagonizes cortisol action competitively at the receptor level

Shipping

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we have lots of experience of shipping all over the world.

we will choose the most suitable courier to ensure safe arrival

2.Specification：

Item		Specification	Result	Test Method
Active Ingredeints
Assay(As Dried Base,%)		98.5% to 101%	99.68%	HPLC
Physical Control
Appearance		Crystalline Powder	Complies
Color		White to Colourless	Complies
Odor &Taste		Characteristic	Complies	Organoleptic
Identification		Positive	Complies	IR&1H NMR
Loss on Drying		≤1.0%	0.35%	USP
Melting point		97°C-98°C	97°C-98°C	USP
Residue on ignition		≤0.5%	0.08%	USP
Chemical Control
Heavy metals (As Pb)		NMT20PPM	Conforms	USP
Related substance		Meet the requirements	Conforms	USP
Packing and Storage
Packing	Pack in paper-drums and two plastic-bags inside. 25kg/drum
Storage	Store in a well-closed container away from moisture and direct sunlight.
Shelf Life	3 years if sealed and stored properly.

3.Application：

Drospirenone is an ingredient in some birth control pills and hormone replacement therapy. In combination with ethinyl estradiol it is used ascontraception, and for women who want contraception it is also approved by the U.S. Food and Drug Administration (FDA) to treat moderate acne andpremenstrual dysphoric disorder.

4.Package & Storage:

ackaging Detail	0.5kgs/Al-Bottle 1.0kgs/Al- Bottle 2.0kgs/Al- Bottle 5.0 kgs/Al-Bottle 25.0 kgs/drum or upon customers' request.
Storage	Store in a well-closed container away from moisture
Shelf Life	2 years if sealed and store away from direct sun light.
Delivery Detail	within 3 days after get the payment

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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body