2016年9月26日星期一

Bimatoprost


Bimatoprost (marketed in the US, Canada and Europe by Allergan, under the trade name Lumigan) is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes. In December 2008, the indication to lengthen eyelashes was approved by the U.S. Food and Drug Administration (FDA); the cosmetic formulation of bimatoprost is sold as Latisse.
Uses

Medical

Bimatoprost is used for the treatment of open-angle glaucoma and ocular hypertension in adult patients, either alone or in combination with a beta blocker (typically timolol).

Studies have shown bimatoprost to be more effective than timolol in reduction of intraocular pressure (IOP) and as least as effective as the prostaglandin analogs latanoprost and travoprost in reducing IOP.

Cosmetic

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In patients using ophthalmic prostaglandins such as travoprost and latanoprost, it has been noted that there had been an increase in diameter, density and length of eyelashes. A study published in May 2010 found that bimatoprost in a gel suspension, when applied at the base of the upper eyelid eyelashes, significantly increased eyelash length.[citation needed] Allergan initiated clinical trials investigating the usage of bimatoprost as a cosmetic drug. In 2008, the FDA Dermatologic and Ophthalmic Drugs Advisory Committee voted to approve bimatoprost for the cosmetic use of darkening and lengthening eyelashes.The medical term for this is treatment of hypotrichosis; however, the FDA approval is for purely cosmetic purposes.

1 Basic information :
HP1003   EP / USP Standard   CAS 155206-00-1  Bimatoprost  powder
BimatoprostCAS 155206-00-1 Brand: Hyper
MW: 415.57MSDS: Avaiable
MF : C25H37NO4Sample: Avaiable
Category:ProstaglandinMin order: 10grams
Quality standard :EP/USPPlace of Origin:China
IntroductionBimatoprost is a prostaglandin analog/prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes. It has also been used and prescribed off-label to lengthen eyelashes
CharacterWhite powder, bimatoprost powder
ApplicationsPharmaceutical raw materials
2. Quality Specification:  Contact HYPER CHEM  for updated version COA
TESTSPECIFICATIONSRESULTS
AppearanceWhite to yellow crystalline powderWhite crystalline powder
IdentificationA. Should meet the requirementConforms
B. Should meet the requirementConforms
Impurity A≤0.5%N.D.
Impurity B≤0.3%0.075%
Loss on drying≤0.5%0.085%
Residue on Ignition≤0.1%0.045%
Residual solventEthanol≤0.5%0.026%
Ethyl acetate≤0.5%N.D.
Tetrahydrofuran≤0.072%N.D.
Heavy Metal≤20ppmConforms
Assay98.0%~102.0% (Calculated on the dried basis)99%
3 .Packaging & Delivery 
1•  Packaging Detail: 100/bag,500g/bag,1kg/bag,25kg/drum
     Delivery Detail:  According the quantity(Small order:3-5days; Big order:5-15days)
2•Payment terms: T/T 100% in advance by Western union & Company bank account and Paypal(small sample only)
3•  Payment way: We accept payments throught Telex transfer, Paypal, Western Union...
4•  Shipping methods: We offer several delivery services to suit all customer needs. By Courier or Air and Sea, such as: DHL, FEDEX, TNT, UPS, EMS.

my contact infomation is: 
Email: cloris_2016@tuskwei.com or bettytuskwei@yahoo.com
Skype: betty_3451
Website: http://www.tuskwei.net/


Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body

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