显示标签为“Stimulants”的博文。显示所有博文
显示标签为“Stimulants”的博文。显示所有博文

2016年9月5日星期一

Bupropion


Bupropion is a medication primarily used as an antidepressant and smoking cessation aid. It is marketed asWellbutrin and Zyban among other trade names. It is one of the most frequently prescribed antidepressants in the United States and Canada, although in many countries this is an off-label use. Bupropion is taken in tablet form and is available only by prescription in most countries.
Product Name:Bupropion
Synonyms:(+-)-1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone;1-dimethylethyl)amino)-1-(3-chlorophenyl)-2-(((+-)-1-propanon;alpha-(tert-butylamino)-m-chloropropiophenone;Wellbutrin1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino)-1-propamone;BUPROPION HCL;DL-1-(3-CHLOROPHENYL)-2-[(1,1-DIMETHYLETHYL)AMINO]-1-PROPANONE HYDROCHLORIDE;AMFEBUTAMONE;AMFEBUTAMONE HCL
Superiority
Product Name:Bupropion
Synonyms:(+-)-1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone;1-dimethylethyl)amino)-1-(3-chlorophenyl)-2-(((+-)-1-propanon;alpha-(tert-butylamino)-m-chloropropiophenone;Wellbutrin1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino)-1-propamone;BUPROPION HCL;DL-1-(3-CHLOROPHENYL)-2-[(1,1-DIMETHYLETHYL)AMINO]-1-PROPANONE HYDROCHLORIDE;AMFEBUTAMONE;AMFEBUTAMONE HCL
CAS:34911-55-2
MF:C13H18ClNO
MW:239.74
EINECS: 
Product Categories:APIs;Isotope
Mol File:34911-55-2.mol
Details
mp233-234°C
solubilityethanol: 193 mg/mL solutions may be stored for several days at 4 °C.
formsolid
colorwhite
CAS DataBase Reference34911-55-2(CAS DataBase Reference)
  
Safety information
Hazard CodesXn
Risk Statements22
Safety Statements36
WGK Germany3
RTECSUG8858000
HazardClassIRRITANT

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2016年9月4日星期日

Oxiracetam



company's website

Oxiracetam (ISF 2522) is a nootropic drug of the racetam family and very mild stimulant. Several studies suggest that the substance is safe even when high doses are consumed for a long period of time.

Details
 
 
【Density】
1.416 g/cm3
【Melting Point】
165-168 °C
【Boiling Point】
494.6 °C at 760 mmHg
【Flash Point】
252.9 °C
【Solubilities】
Soluble
【Storage temp】
2-8°C
【Computed Properties】
Molecular Weight:158.1552 [g/mol]
Molecular Formula:C6H10N2O3
XLogP3-AA:-2.2
H-Bond Donor:2
H-Bond Acceptor:3
Rotatable Bond Count:2
Tautomer Count:6
Exact Mass:158.069142
MonoIsotopic Mass:158.069142
Topological Polar Surface Area:83.6
Heavy Atom Count:11
Formal Charge:0
Complexity:192
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:1
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Feature 3D Acceptor Count:3
Feature 3D Donor Count:2
Feature 3D Ring Count:1
Effective Rotor Count:2.8
Conformer Sampling RMSD:0.6
CID Conformer Count:10
 
Oxiracetam CAS62613-82-5   Specifications:
Test ItemsSpecificationResults
DescriptionWhite to off white crystalline powderComply
Melting point166-170°C167.3-168.1°C
IdentificationPositive reactionPositive reaction
Related substances≤1.0%0.16%
Loss on drying≤0.5%0.06%
Residue on ignition≤0.1%0.02%
Chloride≤0.014%<0.014
Heavy Metals≤20ppm<20ppm
Clarity of solutionConform to standardComplies
Microbial Limit≤20ppm<20ppm
Assay≥99.0%
99.12%
 

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Methiopropamine (MPA)







Methiopropamine (MPA) is a thiophene ring-based structural analog of methamphetamine originally reported in 1942. Chemically it is not a phenethylamine or amphetamine and is not their functional analog either. It originally appeared for public sale in the UK in December 2010 as a "research chemical" or "legal high", recently branded as Blow. It has limited popularity as a recreational stimulant.
Pharmacology
Methiopropamine functions as a selective norepinephrine-dopamine reuptake inhibitor that is approximately 1.85 times more selective for norepinephrine than dopamine. It is approximately one third as potent as dextroamphetamine as a norepinephrine reuptake inhibitor and one fifth as much as a dopamine reuptake inhibitor. It displays negligible activity as a serotonin reuptake inhibitor.
 
Metabolism
 
Methiopropamine metabolism is somewhat similar to methamphetamine. Hydroxylation, demethylation and deamination are in common. Formation of thiophene S-oxide is different, as is the end product which will probably be (substituted) thiophene-2-carboxylic acid. It is then excreted in urine. Compounds on red are inactive.
For N-alkyl amphetamines, deamination and N-dealkylation are the major elimination pathways and renal excretion is a minor one. Methiopropamine is metabolized into active thiopropamine, 4-hydroxymethiopropamine and thiophene S-oxides. These N-demethylated metabolites are further deaminated by the cytochrome P450 enzyme CYP2C19 in the liver transforming them into inactive 1-(thiophen-2-yl)-2-propan-2-one which can be seen as a phenylacetone derivative.[9][10]
 
Thiophene-2-carboxylic acid is the final major metabolic product. It is very hydrophilic and is excreted in urine. Methiopropamine and especially thiopropamine are also excreted renally, unchanged.
 
Product Details:
 
ProName:Methiopropamine
 
Appearance:crystals
 
Purity: >99.4%
 
Package: 1kg/foil bag or according to the customers requirements.
 
Application: For chemical research
 
Transportation: SEA OR AIR
 
MOQ: 10 Gram
 
orgin country:China
 
Package: 1kg/foil bag or according to the customers requirements.
 
Storage: Store in a cool dry place and keep away from direct strong light
 
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Nitracaine





Nitracaine is a stimulant with local anesthetic properties that has been sold online as a designer drug.
It is closely related to dimethocaine.
 
Details
 
IUPAC: (3-Diethylamino-2,2-dimethylpropyl)-4-nitrobenzoate
Formula: C16H24N2O4
Mol.mass: 308.37 g/mol
Purity: 99.9% above
Appearance: yellow crystal
Package: Aluminum foil bag
 
TECHNICAL INFORMATION
Formal Name3-(diethylamino)-2,2-dimethylpropyl 4-nitrobenzoate
CAS Number1648893-21-3
Molecular FormulaC16H24N2O4
Formula Weight308.4
Purity≥98%
FormulationA crystalline solid
λmax259 nm
SMILESCC(CN(CC)CC)(C)COC(C1=CC=C([N+]([O-])=O)C=C1)=O
InChI Code1S/C16H24N2O4/c1-5-17(6-2)11-16(3,4)12-22-15(19)13-7-9-14(10-8-13)18(20)21/h7-10H,5-6,11-12H2,1-4H3
InChI KeySPTIETJWCCCJSE-UHFFFAOYSA-N
WARNING - This product is not for human or veterinary use.
SHIPPING & STORAGE
Storage-20°C
ShippingWet ice in continental US; may vary elsewhere
StabilityAs supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly

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