Ofloxacin

Ofloxacin is an antibiotic useful for the treatment of a number of bacterial infections. When taken by mouth or injection into a vein this includes pneumonia, cellulitis, urinary tract infections, prostatitis, plague and certain types of infectious diarrhea. Other uses, along with other medications, include multidrug resistant tuberculosis. An eye drop may be used for a superficial bacterial infection of the eye and an ear drop may be used for otitis media when there is a hole in the ear drum.

When taken by mouth common side effects include vomiting, diarrhea, headache, and rash. Other serious side effect include tendon rupture, numbness due to nerve damage, seizures, and psychosis. Use in pregnancy is typically not recommended. Ofloxacin is in the fluoroquinolone family of medications. It works by interfering with the bacteria's DNA.

Ofloxacin was patented in 1980 and approved for medical use in 1985. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Ofloxacin is available as a generic medication.

Medical uses

In the U.S. ofloxacin is approved for the treatment of bacterial infections such as:

Acute bacterial exacerbations of chronic bronchitis

Community-acquired pneumonia

Uncomplicated skin and skin structure infections

Nongonococcal urethritis and cervicitis

Mixed Infections of the urethra and cervix

Acute pelvic inflammatory disease

Uncomplicated cystitis

Complicated urinary tract infections

Prostatitis

Acute, uncomplicated urethral and cervical gonorrhea.

Ofloxacin has not been shown to be effective in the treatment of syphilis. Floxin is no longer considered a first line treatment for gonnorrhea due to bacterial resistance.

Product Description:

Product Name: Ofloxacin

Appearance: White powder

Content: 99%Min

CAS #: 82419-36-1

Test Method: HPLC

Molecular Formula: C18H20FN3O4

Molecular Mass: 361.37

Certificate of Analysis

Item	Standard	Result
Appearance	White to Light Yellowish Crystalline Powder	Conform
Identification	Meets Requirement	Conform
Specific Rotation	-1º - +1º	0 º
Purity Test (HPLC) A: Individual impurity B:Total impurity	≤0.3% ≤0.5%	0.1% 0.2%
Loss on Drying	≤0.20%	0.08%
Residue on Ignition	≤0.10%	0.04%
Heavy Material	≤0.001%	＜0.001%
Arsenic	≤0.0011%	Conform
Residual Solvents A:Methanol B:Ethanol	≤0.005% ≤0.05%	0.002% 0.005%
Assay	98.5%-101.5%	99.46%

Usage: Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.

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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body