2017年3月6日星期一

ADENINE RIBOSIDE

Adenosine is a purine nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond. Adenosine is widely found in nature and plays an important role in biochemical processes, such as energy transfer—as adenosine triphosphate (ATP) and adenosine diphosphate (ADP)—as well as in signal transduction as cyclic adenosine monophosphate (cAMP). It is also a neuromodulator, believed to play a role in promoting sleep and suppressing arousal. Adenosine also plays a role in regulation of blood flow to various organs through vasodilation.

In addition to adenosine's endogenous forms, it is also used as a medication, specifically, as an antiarrhythmic agent, to treat a number of forms of supraventricular tachycardia that do not improve with vagal maneuvers. Common side effects include chest pain, feeling faint, shortness of breath along with tingling of the senses . Serious side effects include a worsening dysrhythmia and low blood pressure. It appears to be safe in pregnancy.

Adenosine – cosmetics grade
Product No.: SB001-1
CAS No.: 58-61-7
Other name:Adenine riboside
Synonyms: D-ADENOSINE;AR;(2R,3R,4S,5R)-2-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL;9-BETA-D-RIBOFURANOSYLADENINE;ADENINENUCLEOSIDE;ADENINE RIBOSIDE;ADENOSINE;ADENINE-9-BETA-D-RIBOFURANOSIDE
Formular: C10H13N5O4
Molecular weight: 267.24
Appearance: a white or almost white crystalline powder
Loss on drying: ≤1.0%
Assay: ≥99%
Endotoxin: ≤1000EU/g
Total aerobic limits:≤1000cfu/g
Total mold limits:≤100cfu/g
Escherichia coli: Not detected

Application
Adenosine is an endogenous nucleoside throughout the human cells directly into the myocardium by phosphorylation generates adenylate involved in myocardial energy metabolism. Adenosine also attend the expansion of coronary vessels, increasing blood flow.
Adenosine plays a physiological role on the cardiovascular system and the body's many systems and organizations. Adenosine is used in the synthesis adenosine triphosphate, adenosine (ATP), adenine, adenosine, the vidarabine important intermediates.
Packing
25kg/drum or as per your requirement
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Stored in a cool, dry, well-ventilated area. Away from incompatible substances. Store protected from moisture.

Specification of Adenosine 58-61-7
1. Molecular formula: C10H13N5O4
2. Molecular weight: 267.24
3. CAS No.: 58-61-7
4. Melting point: 233-238°C
5. Specific rotation: -68.0°- -72.0°
6. Acidity or alkalinity: complies with USP28
7. Loss on drying: ≤0.5%
8. Residue on ignition: ≤0.1%
9. Heavy metals: ≤0.001%
10. Limit of ammonia: ≤0.0004%
11. Limit of chloride: ≤0.007%
12. Limit of sulfate: ≤0.02%
13. Total impurities: ≤0.5%
14. Each of guanosine, inosine, and uridine ≤0.1%
15. Adenine: ≤0.2%
16. Assay: 99.0-101.0%
17. Complies with USP28
18. Packing: 20kg/barrel
19. Storage: Keep dry, stable at room temperature.
Indexstandards
Assay99%min
Melting point °C-68.0°C to –72.0°C
Acidity or alkalinity
Solution appears blue-violet color and yellow color

Loss on drying,%≤0.5
Heavy metals(Pb), %≤0.001
Limit of ammonia,%≤0.0004
Limit of chloride(Cl),%≤0.007
Limit of sulfate(SO4),%≤0.02
Chromatographic purity, %
Guanosine, %
Inosine, %
Ruidine, %
Adenine, %
Total impurities, %
≤0.1
≤0.1
≤0.1
≤0.2
≤0.5

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Email: bettyapi@aliyun.com or bettyapi1989@yahoo.com
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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body

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