2017年3月6日星期一

Indapamide

Indapamide is a thiazide-like diuretic drug marketed by Servier, generally used in the treatment of hypertension, as well as decompensated heart failure. Combination preparations with perindopril (an ACE inhibitor antihypertensive) are also available.
Indications

Hypertension and edema due to congestive heart failure. Indapamide has been proven in the HYVET trial to reduce stroke and all cause mortality when given with or without perindopril to people over the age of 80 for the treatment of hypertension.

Contraindications

Indapamide is contraindicated in known hypersensitivity to sulfonamides, severe kidney failure, hepatic encephalopathy or severe liver failure, and a low blood potassium level.

There is insufficient safety data to recommend indapamide use in pregnancy or breastfeeding.

Interactions

Caution is advised in the combination of indapamide with lithium and nonantiarrhythmic drugs causing wave-burst arrhythmia (astemizole, bepridil, IV erythromycin, halofantrine, pentamidine, sultopride, terfenadine, vincamine).

Precautions

Monitoring of potassium and uric acid serum levels is recommended, especially in subjects with a predisposition or a sensitivity to hypokalemia and in patients with gout.


1. Specification of (26807-65-8)
Appearance: White or almost white crystalline powder
Identification: Positive
Specific rotation: -0.02 ~ +0.02°
Related substances: Meets the requirements
Water: 1.7%
Sulfate ash: 0.03%
Heavy metals: < 10ppm
Assay: 98 ~ 102%

2. Properties of (26807-65-8)
factory standard
CAS No.: 26807-65-8
MF: C16H16ClN3O3S
EINECS No.: 248-012-7
Type: Pharmaceutical Intermediates
3 Use of (26807-65-8)
The chemical is a non-thiazide sulphonamide diuretic drug marketed by Servier, generally used in the treatment of hypertension, as well as decompensated cardiac failure.
4.Packing : 25kg / drum or according to your requirements .
5.Delivery time : 7-28days after approval .

AppearanceWhite or almost white crystalline powderConforms
IdentificationPositiveConforms
Specific rotation-0.02 ~ +0.02°Conforms
Related substancesMeets the requirementsConforms
Water£ 3.0%1.7%
Sulfate ash£ 0.1%0.03%
Heavy metals£ 10 ppm< 10ppm
Assay98 ~ 102%99.2%

Usage:antibacterial
Storage information: keep away from strong light, high temperature place,Store in Cool and dry .
Transportation:by air express delivery(DHL,FedEx,EMS ect.) or sea shipping (FOB,CIF,CFR,CNF ect.)
Sample:sample can be supplied if you inquiry
Price: we will give you the best price !

Indapamide.jpg

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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body




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