2017年3月2日星期四

Roflumilast

Roflumilast (trade names Daxas, Daliresp) is a drug that acts as a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). It has anti-inflammatory effects and is used as an orally administered drug for the treatment of inflammatory conditions of the lungs such as chronic obstructive pulmonary disease (COPD).
In June 2010, Daxas was approved in the EU for severe COPD associated with chronic bronchitis. In March 2011, Daliresp gained FDA approval in the US for reducing COPD exacerbations.
Medical uses
Its primary clinical use is in the prevention of exacerbations (lung attacks) in severe COPD.
Introduction: 
Place of orgin : China
Specifications:
CAS no. : 162401-32-3
Molecular formula: C17H14Cl2F2N2O3
Molecular weight: 403.2075
Density: 1.471 g/cm3
Melting point: 158 ℃
Boiling point: 430.6 ° C at 760 mmHg
Flash: 214.2 ° C
Vapor pressure: 1.28 e-07 mmHg at 25 ° C
Storage :Store in cool and dry palce. Keep away from strong light ,high temperature.
Usage: Used for pharmaceutical intermediates
transportation:by express delivery (by EMS,DHL,TNT & FEDEX) or sea & air shipping.
Shipment term: EXW, FOB, CIF, CNF
Sample: At any time to provide (lowest price & highest quality)
Product Name:                                                 Roflumilast
CAS RN.:                                                                    162401-32-3
Molecular Weight:                                                     403.2075
Molecular Formula:                                                  C17H14Cl2F2N2O3
Density:                                                                        1.471g/cm3
Melting Point(℃):                                                      158℃
Boiling Point(℃):                                                       430.6°C at 760 mmHg
Flash Point(℃):                                                         214.2°C
refractive_index:                                                         1.603
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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body

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