ETH-LAD

ETH-LAD, 6-ethyl-6-nor-lysergic acid diethylamide is an analogue of LSD. Its human psychopharmacology was first described by Alexander Shulgin in the book TiHKAL. ETH-LAD is a psychedelic drug similar to LSD, and is slightly more potent than LSD itself, with an active dose reported at between 20 and 150 micrograms. ETH-LAD has subtly different effects to LSD, described as less demanding.

Chemistry

ETH-LAD, or 6-ethyl-6-nor-lysergic acid diethylamide, is a semi-synthethic alkaloid of the lysergamide famiy. ETH-LAD is a structural analogue of lysergic acid with an N,N-diethylamide functional group bound to RN of the chemical structure. This core polycyclic structure is an indole derivative and has tryptamine and phenethylamine groups embedded within it. ETH-LAD's structure contains a bicyclic hexahydroindole fused to a bicyclic quinoline group (nor-lysergic acid).

ETH-LAD does not contain a methyl group substituted at R6 of its nor-lysgeric acid skeleton; this is represented by the nor- prefix. Instead, ETH-LAD is substituted at R6 with an ethyl group. At carbon 8 of the quinoline, a N,N-diethyl carboxamide is bound. ETH-LAD is a chiral compound with two stereocenters at R5 and R8. ETH-LAD, also called (+)-D-ETH-LAD, has an absolute configuration of (5R, 8R).

Pharmacology

ETH-LAD likely acts as a 5-HT2A partial agonist. The psychedelic effects are believed to come from ETH-LAD's efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Product name：ETH-LAD

CAS RN.:65527-62-0

Molecular formula：C21H27N3O

Apperance: white powder

Stoage:in shade

Means of Transportation: By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or CNF ect...)

Usage : chemical research

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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body